ABSTRACT
Babesiosis is a protozoal disease caused by members of the genus Babesia transmitted by the ixodid ticks. It is a parasite of various mammalian hosts as bovine [B. bovis], equine [B. equi], rodent [B. microti], canine [B. canis] and others. Human cases of babesiosis have been reported from several countries including Egypt. It is now well established that man may become infected [fulminating or subclinical] with several species of Babesia without prior splenectomy. In this paper, a total of 398 Rattus rattus and 90 R. norvegicus were trapped in Suez, Ismailia, Port-Said, North Sinai and South Sinai governorates. Blood films were taken from the tail after a simple cut of its end. The films were fixed in acetone free methyl alcohol and stained with Giemsa stain as usual. The results showed that all rats trapped in Ismailia had Babesia infection, then decreased in North Sinai, Port-Said, South Sinai and was zero in Suez. As double infection, Trypanosoma lewisi was found in rats trapped in Port-Said, North Sinai and South Sinai. But none had theileria infection. The medical and veterinary importance of these results was discussed